Relationships between Relative Proportion of Tissue Components, Urodynamic Parameters, and Low Urinary Tract Symptoms in Patients with Benign Prostatic Hyperplasia
Korean Journal of Urology
;
: 859-864, 2009.
Article
in Korean
| WPRIM
| ID: wpr-162212
ABSTRACT
PURPOSE:
This study was designed to investigate the relationship between the histological composition of the prostate, preoperative clinical parameters, and the results of transurethral resection of prostate (TURP). MATERIALS ANDMETHODS:
A total of 61 patients with benign prostatic hyperplasia (BPH) who had undergone TURP were enrolled retrospectively. Slides were surveyed for relative areas (%) of glandular epithelium (GE), stroma (ST), and smooth muscle (SM) in stroma by performing immunohistochemistry, and the mean outcomes were calculated with a computer-assisted image analyzer (x200).RESULTS:
Total prostate volume was less than 40 ml in 19 patients (group 1), 40 to 80 ml in 23 patients (group 2), and more than 80 ml in 19 patients (group 3). The percentage of SM was significantly greater in group 1 (29.5+/-4.2%) than in group 3 (23.7+/-3.2%), but GE and ST did not differ significantly. AG number was significantly higher in group 3 than in the other groups but did not correlate with SM. Improvements in International Prostate Symptom Score, which were similar in each group, were positively correlated with SM.CONCLUSIONS:
SM in prostate adenoma is increased in men with a small prostate and may play an important role in lower urinary tract symptoms in small BPH
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostate
/
Prostatic Hyperplasia
/
Urinary Tract
/
Urodynamics
/
Immunohistochemistry
/
Adenoma
/
Retrospective Studies
/
Transurethral Resection of Prostate
/
Epithelium
/
Lower Urinary Tract Symptoms
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Urology
Year:
2009
Type:
Article
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