CD 4+/CD56+ Hematodermic Neoplasm in Infancy: Case Report / 대한피부과학회지
Korean Journal of Dermatology
;
: 1017-1020, 2011.
Article
in Korean
| WPRIM
| ID: wpr-162682
ABSTRACT
CD4+/CD56+ hematodermic neoplasm is a rare and aggressive lesion that affects many organs, and skin involvement is highly characteristic. It is also termed blastic natural killer cell lymphoma in the World Health Organization classification. Several origins of tumor cells have been proposed, but recent studies have shown a relationship with plasmacytoid dendritic cells. A 2-year-old boy presented with multiple bruise-like violaceous subcutaneous nodules and plaques on the trunk, upper and lower extremities. Histological examination showed small-to-medium-sized blastoid cellular infiltration in the dermis and subcutaneous tissue. Tumor cells were positive for CD4, CD56 and TdT, and negative for CD8, CD20 and MPO. It primarily affects elderly patients, but, in this case, occurred in an infant. Due to its rarity, we present a case of CD4+/CD56+ hematodermic neoplasm affecting a pediatric patient.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
World Health Organization
/
Dendritic Cells
/
Killer Cells, Natural
/
Child, Preschool
/
Dermis
/
Lower Extremity
/
Subcutaneous Tissue
/
Lymphoma
Limits:
Aged
/
Humans
/
Infant
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2011
Type:
Article
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