Alternative biomarkers for assessing glycemic control in diabetes: fructosamine, glycated albumin, and 1,5-anhydroglucitol
Annals of Pediatric Endocrinology & Metabolism
;
: 74-78, 2015.
Article
in English
| WPRIM
| ID: wpr-163414
ABSTRACT
The growing attention to alternative glycemic biomarkers including fructosamine, glycated albumin (GA), 1,5-anhydroglucitol (1,5-AG), is attributable to the limitations of the glycated hemoglobin (HbA1c) assay. It is important to recognize the conditions in which HbA1c levels may be difficult to interpret. Serum fructosamine and GA have been proposed useful tools for monitoring of short-term glycemic control. These biomarkers not only reflect well glycemic control in hematologic disorder, but also represent postprandial glucose fluctuation. Serum 1,5-AG may be useful for estimating within-day glucose variation. Use of these nontraditional tests can be more helpful in the management of diabetes as complement traditional measures. Further larger cohort studies are warranted to determine whether nontraditional biomarkers have potential utility for early diagnosis, management of diabetes, and prevention of diabetic complications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Complement System Proteins
/
Glycated Hemoglobin
/
Biomarkers
/
Cohort Studies
/
Fructosamine
/
Early Diagnosis
/
Diabetes Complications
/
Diabetes Mellitus
/
Glucose
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Risk factors
/
Screening study
Language:
English
Journal:
Annals of Pediatric Endocrinology & Metabolism
Year:
2015
Type:
Article
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