Facial palsy as the presenting symptom of acute myeloid leukemia in children: Three cases with stem cell transplantations / 소아과
Korean Journal of Pediatrics
;
: 713-716, 2009.
Article
in English
| WPRIM
| ID: wpr-163688
ABSTRACT
Facial palsy as the presenting symptom of leukemia is very rare, especially in acute myeloid leukemia. A review of the medical literature identified reports on 8 children with AML who had facial paralysis as the presenting sign. Whole brain irradiation (WBI) has been applied in most cases. We present the cases of 3 such children. Achieving a remission without WBI, the patients underwent stem cell transplantations (SCTs). Two patients remain event-free 52 months and 62 months after allotransplants. Facial palsy was the harbinger of leukemic relapse in one case after autotransplant. This patient is disease-free 59 months after unrelated SCT rescue. Facial palsy persisted in 2 cases. Allogeneic SCT without WBI may be an effective therapy in patients presenting with facial palsy. A brief review of the literature is presented here.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Stem Cells
/
Brain
/
Leukemia, Myeloid, Acute
/
Leukemia
/
Stem Cell Transplantation
/
Facial Paralysis
Type of study:
Diagnostic study
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS