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Facial palsy as the presenting symptom of acute myeloid leukemia in children: Three cases with stem cell transplantations / 소아과
Korean Journal of Pediatrics ; : 713-716, 2009.
Article in English | WPRIM | ID: wpr-163688
ABSTRACT
Facial palsy as the presenting symptom of leukemia is very rare, especially in acute myeloid leukemia. A review of the medical literature identified reports on 8 children with AML who had facial paralysis as the presenting sign. Whole brain irradiation (WBI) has been applied in most cases. We present the cases of 3 such children. Achieving a remission without WBI, the patients underwent stem cell transplantations (SCTs). Two patients remain event-free 52 months and 62 months after allotransplants. Facial palsy was the harbinger of leukemic relapse in one case after autotransplant. This patient is disease-free 59 months after unrelated SCT rescue. Facial palsy persisted in 2 cases. Allogeneic SCT without WBI may be an effective therapy in patients presenting with facial palsy. A brief review of the literature is presented here.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Stem Cells / Brain / Leukemia, Myeloid, Acute / Leukemia / Stem Cell Transplantation / Facial Paralysis Type of study: Diagnostic study Limits: Child / Humans Language: English Journal: Korean Journal of Pediatrics Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Stem Cells / Brain / Leukemia, Myeloid, Acute / Leukemia / Stem Cell Transplantation / Facial Paralysis Type of study: Diagnostic study Limits: Child / Humans Language: English Journal: Korean Journal of Pediatrics Year: 2009 Type: Article