A Case of Valganciclovir Treatment for Cytomegalovirus Retinitis
Journal of the Korean Ophthalmological Society
;
: 531-538, 2008.
Article
in Korean
| WPRIM
| ID: wpr-163809
ABSTRACT
PURPOSE:
To report a case of a patient with cytomegalovirus (CMV) retinitis who was treated with oral valganciclovir. CASESUMMARY:
A 34-year-old man who had undergone anti-cancer chemotherapy for Non-Hodgkin lymphoma was referred to the ophthalmologic oncology clinic because of decreased vision in both eyes. Fundus examination showed white, opaque, and granular retinal lesions in both eyes, and a serologic test showed a positive response to CMV antibody IgG and a negative response to CMV antibody IgM. The patient received induction therapy with intravenous ganciclovir and maintenance therapy with oral valganciclovir 900 mg once daily. CMV retinitis reactivated 4 weeks after maintenance therapy was discontinued. At that point, the patient received induction therapy with oral valganciclovir 900 mg twice daily for 3 weeks and maintenance therapy with 900 mg once daily for 5 weeks. The retinal lesion disappeared and did not recur after oral administration of valganciclovir. The patient discontinued valganciclovir after 5 weeks of maintenance therapy, and CMV retinitis did not reactivate during 6 months of follow-up.CONCLUSIONS:
Oral valganciclovir was clinically effective in the treatment of CMV retinitis in a patient who was treated with anti-cancer chemotherapy for non-Hodgkin lymphoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Retinaldehyde
/
Retinitis
/
Vision, Ocular
/
Lymphoma, Non-Hodgkin
/
Immunoglobulin G
/
Immunoglobulin M
/
Serologic Tests
/
Ganciclovir
/
Administration, Oral
/
Follow-Up Studies
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2008
Type:
Article
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