Nucleotide sequence analysis of HTLV-I isolate from a Korean patient with HAM/TSP
Yonsei Medical Journal
;
: 321-327, 1993.
Article
in English
| WPRIM
| ID: wpr-164086
ABSTRACT
Limited nucleotide sequences of human T-cell lymphotropic virus type I (HTLV-1) provirus isolated from the first case of a Korean patient with HTLV-I associated myelopathy and tropical spastic paraparesis (HAM/TSP) were analysed and compared with other isolates from different regions of the world. The sequences of the env, LTR regions (536bp, 690bp respectively) showed 98.7%, 99.3% homologies with the prototype HTLV-I, ATK-1, isolated from a Japanese Adult T-cell leukemia (ATL) patient. A comparison between other isolates from different geographical origins revealed that the Korean HTLV-I isolate is more closely related to Japanese isolates than to those from other geographical origins
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
DNA, Viral
/
Molecular Sequence Data
/
Base Sequence
/
Human T-lymphotropic virus 1
/
Molecular Probes
/
Korea
/
Muscle Spasticity
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Yonsei Medical Journal
Year:
1993
Type:
Article
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