Intracavernosal Self-Injection Therapy for the Patients with Erectile Dysfunction: Comparison of Erectile Response and Complications between Bimix and Trimix Solution / 대한비뇨기과학회지
Korean Journal of Urology
;
: 306-311, 1997.
Article
in Korean
| WPRIM
| ID: wpr-164737
ABSTRACT
PURPOSE:
To compare the efficacy of Bimix solution (27.3 mg/ml papaverine and 0.9 mg/ml phentolamine) versus Trimix solution (18.8 mg/ml papaverine, 0.6 mg/ml phentolamine and 6.3ug/ml prostaglandin El) in terms of erectile response and complications. MATERIALS ANDMETHODS:
We comparatively analyzed the erectile response and the incidence of pain, prolonged erection (>4 hours), and corporal fibrosis of either medication in the 155 impotent patients who used Bimix solution for intracavernous pharmacotherapy (mean duration 15 months) and thereafter used Trimix solution (mean 12 months).RESULTS:
Erectile response to Trimix solution was significantly better than Bimix solution (p<0.01). The mean dose of Bimix solution was higher than Trimix solution (0.43 ml. vs. 0.34 ml, p<0.05). The severe pain enough for impediment to ntercourse occurred in 6.5% of the Trimix group, while no patient of the Bimix group experienced (p<0.01). The corporal fibrosis was noted in 8.4% of the Trimix group and 16.1% of the Bimix group. However, there was no significant difference between the two groups (p=0.08). The incidence of prolonged erection was significantly lower (p<0.05) in the Trimix group (2.6%) than in the Bimix group (12.3%). A total of 139 patients (89.7%) finally selected Trimix solution.CONCLUSIONS:
The Trimix solution was more effective and safer than Bimix solution for the treatment of erectile dysfunction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papaverine
/
Phentolamine
/
Fibrosis
/
Incidence
/
Drug Therapy
/
Erectile Dysfunction
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Urology
Year:
1997
Type:
Article
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