Comparative Analysis of Squamous Cell Differentiation by Histologic Subtypes in Basal Cell Carcinoma / 대한피부과학회지
Korean Journal of Dermatology
;
: 1475-1481, 2005.
Article
in Korean
| WPRIM
| ID: wpr-165575
ABSTRACT
BACKGROUND:
There has been no general agreement on classifying basal cell carcinoma (BCC), and little is known about the squamous cell differentiations of each subtype of BCC. BCC is a locally-invasive tumor, but its aggressive forms tend to recur and metastasize.OBJECTIVE:
We have compared the histolopathological subtypes of BCC by squamous differentiation, with special emphasis on basosquamous carcinoma and the difference between the non- aggressive and aggressive forms of BCC. MATERIALS ANDMETHOD:
A total of 87 BCC specimens were collected from the 7 branch hospitals of The Catholic University of Korea from July 1997 to June 2003.RESULTS:
1. The 87 samples were divided into 6 subtypes 18 nodular, 19 nodular infiltrative, 12 micronodular, 14 infiltrative, 11 morpheaform, 13 basosquamous. Overall, 18 samples were classified as non- aggressive and the remaining 69 as aggressive. 2.In nodular-infiltrative BCC and basosquamous carcinoma, squamous cell differentiation was significantly more prominent than in the nodular BCC.CONCLUSION:
Squamous cell differentiation should be considered as one of the aggressive markers, especially in nodule-forming BCC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Carcinoma, Basal Cell
/
Carcinoma, Basosquamous
/
Cell Differentiation
/
Hospitals, Satellite
/
Korea
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2005
Type:
Article
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