A Case of Churg-Strauss Syndrome Showing Hemorragic Bullae / 대한피부과학회지

ABSTRACT

A 61-year old woman was presented with various sized, tense and hemorrhagic bullae on the extremities with edema for 10 days. She had a history of bronchial asthma and had a tingling sensation on both legs. Laboratory findings showed leukocytosis, hypereosinopilia and p-ANCA(+). Chest radiograph showed patchy infiltrations in the left upper lobe. Water's view showed bilateral maxillary antral mucosal thickening. Electromyography showed polyneuropathy on both lower legs. Histopathologically, there were conspicuous infiltration of eosinophils within bulla and around vessels in the dermis and radially distributed histiocytes in the degenerated collagen. Treatment with prednisolone 30 mg per day showed a dramatic improvement in symptoms.