Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children / 소아과
Korean Journal of Pediatrics
;
: 271-275, 2016.
Article
in English
| WPRIM
| ID: wpr-166337
ABSTRACT
PURPOSE:
A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients.METHODS:
The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups.RESULTS:
Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05).CONCLUSION:
This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-wave abnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-wave abnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Immunoglobulins
/
Reflex, Abnormal
/
Incidence
/
Prevalence
/
Retrospective Studies
/
Guillain-Barre Syndrome
/
Fever
/
H-Reflex
Type of study:
Incidence study
/
Observational study
/
Prevalence study
/
Prognostic study
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2016
Type:
Article
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