Experience with Bilateral Risk-Reducing Mastectomy for an Unaffected BRCA Mutation Carrier / 한국유방암학회지
Journal of Breast Cancer
;
: 218-221, 2016.
Article
in English
| WPRIM
| ID: wpr-166628
ABSTRACT
Women with BRCA1/2 mutations have a high risk of breast cancer and may opt for risk-reducing mastectomy (RRM). We report a 38-year-old Japanese woman who was diagnosed as a BRCA2 mutation carrier. She underwent prophylactic bilateral skin-sparing mastectomy (SSM) with excision of the nipple and preservation of the areola skin. It is unclear whether a bilateral RRM leads to better survival compared with intensive surveillance. The oncological risk associated with the presence of remnant breast glandular tissue after SSM or nipple-sparing mastectomy has been obscure. We report the first case of RRM for a Japanese BRCA mutation carrier and provide a literature review on risk management for BRCA mutation carriers with a focus on the concepts and procedures of RRM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Risk Management
/
Skin
/
Breast
/
Breast Neoplasms
/
Mastectomy, Subcutaneous
/
Asian People
/
Prophylactic Surgical Procedures
/
Mastectomy
/
Nipples
Type of study:
Etiology study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Journal of Breast Cancer
Year:
2016
Type:
Article
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