MR Findings of Acute Graft-versus-Host Disease Involving Gastrointestinal Tracts
Journal of the Korean Radiological Society
;
: 373-378, 2002.
Article
in Korean
| WPRIM
| ID: wpr-166744
ABSTRACT
PURPOSE:
To evaluate the MR findings of gastrointestinal graft-versus-host disease (GVHD) after allogenic bone marrow transplantation. MATERIALS ANDMETHODS:
Five patients (MF=32, age range 9-58 years) with suspected gastrointestinal GVHD underwent abdominal MRI, and the findings were evaluated. Because of acute myelocytic leukemia (n=4) or non-Hodgkin's lymphoma (n=1), all had undergone allogenic bone marrow transplantation 2-6 (mean, 3.5) weeks earlier. T2-weighted half-Fourier acquisition snapshot turbo spin-echo, T1-weighted spoiled gradientecho (SGE), and postcontrast T1-weighted SGE MR imaging, with and without fat-suppression, was performed.RESULTS:
All five patients showed bowel wall thickening and marked contrast enhancement in the jejunum (n=5), ileum (n=4), duodenum (n=3), sigmoid colon (n=3), gastric antrum (n=2), and rectum (n=2). Bowel wall thickening showed a target appearance in the jejunum (n=2, 40.0%), ileum (n=1, 25.0%), sigmoid colon (n=1, 33.3%), and rectum (n=1, 50.0%), while the remaining cases showed diffuse wall thickening without layering. Small amount of ascites was noted in four patients (80%), and multiple small conglomerated retroperitoneal lymph nodes in three (60%). In all patients, a signal intensity of slightly enlarged liver due to iron overload secondary to multiple blood transfusions, gave rise to decreased signal intensity at both T1-and T2-weighted MR imaging.CONCLUSION:
In patients with GVHD, the commonly noted MR findings were bowel wall thickening with contrast enhancement, ascites and retroperitoneal lymphadenopathy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ascites
/
Pyloric Antrum
/
Rectum
/
Colon, Sigmoid
/
Blood Transfusion
/
Lymphoma, Non-Hodgkin
/
Magnetic Resonance Imaging
/
Leukemia, Myeloid, Acute
/
Bone Marrow Transplantation
/
Iron Overload
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Radiological Society
Year:
2002
Type:
Article
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