A Case of Amniotic Membrane Transplantation for Corneal Injury induced by Gramoxone(R)

ABSTRACT

PURPOSE: We report a case of corneal burn induced by Gramoxone(R), treated successfully with amniotic membrane transplantation. METHODS: A 68-year-old female patient was diagnosed as corneal burn induced by Gramoxone(R) and referred from other hospital after treatment at local clinic for 2 weeks. Severe conjunctival injection, chemosis of palpebral conjunctiva, fibrovascular invasion on nasal side of limbus and cornea, corneal opacity, stromal edema with Descement membrane folding were observed. We performed amniotic membrane transplantation. RESULTS: There were no corneal opacity, symblepharon and lacrimal punctal occlusion on the last follow up after 13 months until operation. Only partial pseudopterygium was found at the inferior nasal portion of cornea and limbus. Corneal thickness of margin of the lesion was 803 um. Refrective examination showed astigmatism, -0.9D, axis 5degrees. Final visual acuity was 0.8 (corrected, 1.0). CONCLUSIONS: Amniotic membrane transplantation was simple, short in operation time, no need of additional procedures and it prevents corneal opacity, edema and neovascularization of limbus then, promotes re-epitheliarization of cornea and recovers visual acuity normally in this case.