Biopsy-Proven Immune Complex Glomerulonephritis Associated with Sunitinib in a Patient with a Gastrointestinal Stromal Tumor / 대한신장학회지
Korean Journal of Nephrology
;
: 644-649, 2010.
Article
in English
| WPRIM
| ID: wpr-168912
ABSTRACT
Sunitinib, a multi-targeted tyrosine kinase inhibitor, is used for the treatment of renal cell carcinoma and gastrointestinal stromal tumors. Many adverse effects associated with sunitinib, including hypertension, proteinuria, and thrombotic microangiopathy, have been reported; however, the other forms of glomerulonephritis are very rare. We report a case of biopsy-confirmed immune complex glomerulonephritis in a patient with a gastrointestinal tumor who received sunitinib treatment. The proteinuria subsided partially after sunitinib was discontinued, but when the drug was reintroduced, it recurred.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Pyrroles
/
Protein-Tyrosine Kinases
/
Carcinoma, Renal Cell
/
Gastrointestinal Stromal Tumors
/
Thrombotic Microangiopathies
/
Glomerulonephritis
/
Hypertension
/
Indoles
/
Antigen-Antibody Complex
Limits:
Humans
Language:
English
Journal:
Korean Journal of Nephrology
Year:
2010
Type:
Article
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