A Case of Schizophrenia with Periventricular Leukomalacia on Magnetic Resonance Imaging / 신경정신의학
Journal of Korean Neuropsychiatric Association
;
: 256-259, 2010.
Article
in Korean
| WPRIM
| ID: wpr-169078
ABSTRACT
Schizophrenia was once known as a functional psychosis, a disorder with no structural basis. However, nowadays research has identified and confirmed many structural abnormalities in schizophrenia. One prominent such feature is the combination of ventricular enlargement and decreased cerebral volume. Periventricular leukomalacia causes cerebral palsy, cognitive impairment, visual impairment, and seizures. Recent studies reveal that periventricular leukomalacia causes ventricular enlargement and many brain circuit disruptions. Ventricular enlargement caused by periventricular leukomalacia is the most common pathological marker of schizophrenia. In this study, we report a case with periventricular leukomalacia on MRI findings in a 28-year-old schizophrenia patient. This patient showed auditory hallucinations and somatic delusions. We highlight the structural abnormalities, especially periventricular leukomalacia, in this case of schizophrenia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psychotic Disorders
/
Schizophrenia
/
Seizures
/
Vision Disorders
/
Leukomalacia, Periventricular
/
Brain
/
Magnetic Resonance Imaging
/
Magnetic Resonance Spectroscopy
/
Cerebral Palsy
/
Delusions
Type of study:
Prognostic study
Limits:
Adult
/
Humans
/
Infant, Newborn
Language:
Korean
Journal:
Journal of Korean Neuropsychiatric Association
Year:
2010
Type:
Article
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