Comparison of 99mTc-tetrofosmin and 99mTc-sestamibi Myocardial Perfusion SPECT in Detecting Coronary Artery Fisease / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 137-142, 1998.
Article
in Korean
| WPRIM
| ID: wpr-169340
ABSTRACT
PURPOSE:
Tc-99m-tetrofosmin(TF) is a recently proposed myocardial imaging agent which has similar biokinetic characteristics to Tc-99m-sestamibi(MIBI). The aim of this study was to compare TF and MIBI myocardial perfusion SPECTs in detecting coronary artery disease. MATERIALS ANDMETHODS:
One hundred and sixty patients(l0l males, 59 females, mean age 57+/-9 yr) who had undergone both myocardial perfusion SPECT (M- SPECT) and coronary angiography within 1 month were studied. M-SPECT was performed using TF in 115 patients and MIBI in 45 patients. Stress-rest one day protocol was used in all patients A coronary stenosis was considered significant when the luminal diameter > or =50% was compromised. The chi square test was used to compare, differences in sensitivity and specificity between the two groups.RESULTS:
There was no difference in age and diseased coronary artery branches between the two groups. There were more male patients in TF group Male-to-female ratios of TF and MIBI groups were 7837 and 2322, respectively (p<0.05). The overall sensitivity of TF study was 92% and specificity 36%. The overall, sensitivity and specificity of MIBI study were 93% and 30% respectively. There was no difference between TF and MIBI groups in identifying individual diseased coronary artery branches.CONCLUSION:
One day stress-rest myocardial SPECT using either TF or MIBI was comparable and was a very sensitive test in detecting coronary artery disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Perfusion
/
Phenobarbital
/
Coronary Artery Disease
/
Tomography, Emission-Computed, Single-Photon
/
Sensitivity and Specificity
/
Coronary Angiography
/
Technetium Tc 99m Sestamibi
/
Coronary Vessels
/
Coronary Stenosis
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
1998
Type:
Article
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