Thromboembolism during pregnancy or postpartum / 대한내과학회지
Korean Journal of Medicine
;
: 658-664, 2008.
Article
in Korean
| WPRIM
| ID: wpr-169547
ABSTRACT
BACKGROUND/AIMS:
Venous thromboembolism (VTE) during pregnancy or postpartum is a major cause of maternal complications and death; however, the risk is uncertain. In this study, we sought to estimate the incidence of VTE during pregnancy and to identify risk factors for pregnancy-related VTE.METHODS:
We retrospectively evaluated the incidence, risk factors, treatment, and prognosis for VTE based on 40,989 deliveries at Cheil General Hospital, Kwandong University College of Medicine, over a five-year period from February 2003 to January 2008. The risk factors were analyzed by chi-square-analysis and forward stepwise logistic regression, and are presented as crude and adjusted odds ratios (ORs) with a 95% confidence interval (CI).RESULTS:
The incidence of VTE was 0.042% (17 patients, mean age 32.4+/-2.5 years), with deep venous thrombosis (DVT) in 0.01% of the patients (4 patients, mean age 31.5+/-2.9 years), and pulmonary embolism (PE) in 0.032% of the patients (13 patients, mean age 32.6+/-2.5 years). The postnatal incidence of VTE was higher than the antenatal incidence (2 vs. 15). The main manifestations at the time of diagnosis, in order of frequency, were dyspnea in 8 patients (62%), chest pain in 4 patients (31%), cough in 2 patients (15%), and syncope in 1 patient (8%). The risk factors for VTE were Cesarean section (OR=7.4; 95% CI 2.1-25.7, p=0.002) and preeclampsia (OR=12.0; 95% CI 4.2-34.2, p<0.000). All cases showed clinical improvement spontaneously, or with anticoagulation and surgical thrombectomy, and caused no fetal or maternal mortality.CONCLUSIONS:
The incidence of VTE during pregnancy was 0.042%; the independent risk factors were Cesarean section and preeclampsia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pre-Eclampsia
/
Prognosis
/
Pulmonary Embolism
/
Syncope
/
Thromboembolism
/
Chest Pain
/
Logistic Models
/
Odds Ratio
/
Cesarean Section
/
Maternal Mortality
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2008
Type:
Article
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