Inflammatory Fibroid Polyp of the Stomach Associated with Gastritis Cystica Profunda / 대한소화기내시경학회지

ABSTRACT

Inflammatory fibroid polyp(IFP) typically prescnts as a polypoid mass in the gastric antrum. Radiologically and endoscopically, it can be confused with polypoid carcinoma or submucosal stromal tumor. The histogenetic origin of IFP has been controversial, but it is considered as a reactive lesion of the myofibroblastic nature. IFP is rarely concomitant with gastritis cystica profunda(GCP) which is also one of the nonneoplastic inflammatory polyps. We report a case of IFP associated with GCP presenting as a large polypoid mass in the previously unoperated stomach of a 78-year-old woman. The mass was mainly located in the submucosa of the antrum and the cut surface exhibited a myxoid and glistening appearance with partial cystic change. Histologically, the mass showed marked proliferation of spindle cells, small blood vessels and many inflammatory cells, especially eosinophils. Also, there were many variable sized glands composed of gastric foveolar epithelia within the mass. In conclusion, the rarity of these two associated lesions in the present case may cause difficulty in diagnosis, and therefore recognition about these lesions is needed. In addition, this case supports the nature of IFP as being reactive rather than neoplastic.