Usefulness of Reagent Strips for the Diagnosis of Spontaneous Bacterial Peritonitis / 대한간학회지
The Korean Journal of Hepatology
;
: 243-249, 2005.
Article
in Korean
| WPRIM
| ID: wpr-170399
ABSTRACT
BACKGROUND/AIMS:
Spontaneous bacterial peritonitis (SBP) is one of the potentially life-threatening complications for patients with liver cirrhosis, and it has a mortality rate of over 20%. Early diagnosis of SBP and immediate use of an adequate antibiotic therapy are very important for achieving a better prognosis. The aim of our study was to assess the usefulness of reagent strips for making the rapid diagnosis of SBP.METHODS:
A diagnostic paracentesis procedure was performed upon hospital admission in 257 cirrhotic patients (187 males, 70 females; mean age 54 years) with ascites. Each fresh sample of ascitic fluid was tested using a reagent strip, and the result was scored as 0, 1+, 2+ or 3+. The leukocyte count, polymorphonuclear cell count, blood bottle culture, and chemistry of ascites were also done.RESULTS:
We diagnosed 79 cases of SBP and 2 cases of secondary bacterial peritonitis by means of the polymorphonuclear cell count and the classical criteria. When a reagent strip result of 3+ was considered positive, the test's sensitivity was 86% (70 of 81), the specificity was 100% (176 of 176), and the positive predictive value was 94%. Furthermore, when a reagent strip result of 2+ or more was considered positive, the test sensitivity was 100% (81 of 81), the specificity was 99% (174 of 176), and negative predictive value was 99%.CONCLUSIONS:
The use of reagent strips is a very sensitive and specific tool for the rapid diagnosis of SBP in cirrhotic patients. A positive result should be an indication for empirical antibiotic therapy, and a negative result may be useful as a screening test to exclude SBP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peritonitis
/
Reagent Strips
/
Bacterial Infections
/
English Abstract
/
Ascitic Fluid
/
Predictive Value of Tests
/
Sensitivity and Specificity
/
Liver Cirrhosis
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Korean Journal of Hepatology
Year:
2005
Type:
Article
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