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Prognostic value of serum CA-125 in patients with advanced epithelial ovarian cancer followed by complete remission after adjuvant chemotherapy
Obstetrics & Gynecology Science ; : 29-35, 2013.
Article in English | WPRIM | ID: wpr-170622
ABSTRACT

OBJECTIVE:

The aim of this study was to evaluate the prognostic value of serum CA-125 in advanced epithelial ovarian cancer with complete remission after primary adjuvant chemotherapy.

METHODS:

We reviewed the records of 120 patients with advanced epithelial ovarian cancer who underwent primary surgery followed by adjuvant therapy at our institution between January 1998 and December 2005.

RESULTS:

The median progression free survival was 21.6 months and 12.5 months in patients with nadir CA-125 levels 35 U/mL, respectively, after first cycle of adjuvant chemotherapy.

CONCLUSION:

Serum CA-125 level after the first cycle of adjuvant chemotherapy is a strong independent prognostic factor for advanced epithelial ovarian cancer with complete response.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Ovarian Neoplasms / ROC Curve / Chemotherapy, Adjuvant / Neoplasms, Glandular and Epithelial / Disease-Free Survival Type of study: Prognostic study Limits: Humans Language: English Journal: Obstetrics & Gynecology Science Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Ovarian Neoplasms / ROC Curve / Chemotherapy, Adjuvant / Neoplasms, Glandular and Epithelial / Disease-Free Survival Type of study: Prognostic study Limits: Humans Language: English Journal: Obstetrics & Gynecology Science Year: 2013 Type: Article