Clinicopathologic characteristics and prognostic factors of adenocarcinoma of the uterine cervix: a study of 80 cases / 부인종양
Korean Journal of Gynecologic Oncology
;
: 121-128, 2006.
Article
in Korean
| WPRIM
| ID: wpr-170738
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate the clinicopathologic findings, treatment, and prognostic factors of adenocarcinoma of the uterine cervix.METHODS:
This study retrospectively reviewed 80 patients with histologically proven stage I, II, and III cervical adenocarcinoma, at the Department of Obstetrics and Gynecology of Korea University Anam, Guro, and Ansan Hospitals, between January 1990 and December 2005, for clinical profiles and survival. Survival was analyzed according to the Kaplan-Meier method. Univariate analysis of prognostic factors was performed with the test of log rank. Cox regression model was used in multivariate analysis of prognostic factors.RESULTS:
The mean age at the time of diagnosis was 48.5 years (range 28-81 years) and the most common presenting symptom was uterine bleeding (51.3%). Fifty-eight patients (72.5%) presented with stage I, nineteen (23.7%) with stage II, and three (3.8%) with stage III. Surgery was the main treatment for stage I and IIa and radiation therapy for stage IIb or more. The 5-year survival rates for stages I, II, and III were 85.0%, 63.8%, and 0.0%, respectively. Univariate analysis showed that stage, lymph node metastasis, and lymph-vascular space invasion were significant prognostic factors (p or =50) were significant independent predictors for poor survival (OR 37.352, CI 3.167-440.579; OR 9.823, CI 1.808-53.354, respectively).CONCLUSION:
The results suggest that FIGO stage and age are significant independent prognostic factors for patients with adenocarcinoma of the uterine cervix.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Uterine Hemorrhage
/
Adenocarcinoma
/
Cervix Uteri
/
Multivariate Analysis
/
Survival Rate
/
Retrospective Studies
/
Diagnosis
/
Gynecology
/
Korea
/
Lymph Nodes
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Gynecologic Oncology
Year:
2006
Type:
Article
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