Prevalence of Epstein-Barr Virus(EBV) Antibody in Korean Children
Journal of the Korean Pediatric Society
;
: 804-811, 1994.
Article
in Korean
| WPRIM
| ID: wpr-170745
ABSTRACT
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15 years old. And the results were as follows; 1) The positive rates of anti-VCA IgG 100% in newborn, 90% in 2 to 6 months, 20% in 7 to 12 months, 60% in 1 to 2 years, 77.3% in 3 to 4 years, 88.5% in 5 to 6 years, 90% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively. 2) The anti-VCA IgG titers ranged from 120 to 11280. 3) The positive rates of anti-EBNA were 100% in newborn, 60% in 2 6 months, 10% in 7 to 12 months, 60% in 1 to 2 years, 68.2% in 3 to 4 years, 84.5% in 5 to 6 years, 70% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively. 4) The anti-EBNA titers ranged from 12 to 1128. According to these data, the age of primary infection of EBV has increased compared to the previous data in Korean children.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Immunoglobulin G
/
Capsid
/
Epidemiology
/
Prevalence
/
Herpesvirus 4, Human
/
Epstein-Barr Virus Infections
/
Infectious Mononucleosis
/
Korea
Type of study:
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Child
/
Humans
/
Infant
/
Infant, Newborn
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Pediatric Society
Year:
1994
Type:
Article
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