A Case of Peripheral T-cell Lymphoma Showing Generalized Maculopapular Eruption / 대한피부과학회지

ABSTRACT

In revised WHO classification, "peripheral T-cell lymphoma, unspecified" includes pleomorphic small/medium-sized T cell lymphoma, pleomorphic type and immunoblastic type of CD30+ large cell lymphoma, CD30+ large cell lymphoma by EORTC classification. The skin manifestations of "peripheral T-cell lymphoma, unspecified" can be various, for example, papules, plaques, nodules and erythroderma etc. Of them, generalized maculopapular eruption is known to be rare. A 52-year?old woman presented with widespread erythematous maculopapules on the trunk and extremities. On skin biopsy, there was small to medium-sized lymphocytic infiltration in entire dermis and subcutis. In immunohistochemical staining, the infiltrating cells were: CD3+, CD4+, CD5+, CD45RO+, CD8+, CD30, CD56. Clonal T cell receptor gene rearrangement was present.