Prevalence and distribution of single and multiple HPV infections in cervical cancer and precancerous lesion from Daegu and Gyeongbuk province / 대한산부인과학회지

ABSTRACT

OBJECTIVE: We analysed subtype of HPV infection in cervical cancer and precancerous lesion among women who lived in Daegu and Gyeongbuk province. METHODS: We recruited total of 441 women diagnosed with cytologically abnormal cervical samples between Dec. 2004 and Dec. 2006. We investigated the distribution of HPV subtype and multiple infection according to cervical lesion and age. RESULTS: The most prevalent HPV subtypes in cervical cancer and precancerous lesion were HPV 16, 58, 18, 31, 56 in ASCUS, HPV 16, 58, 52, 66, 18 in LSIL, HPV 16, 58, 33, 52, 18 in HSIL, HPV 16, 58, 33, 52, 53 in IC each other. IC was less multiple infection than ASCUS, LSIL, HSIL. There was strong correlation between the incidence of multiple HPV infection and cervical lesion in young women (<25 years). CONCLUSION: The types of HPV 16, 58, 52, 18 were common in cervical cancer and precancerous lesion from Daegu and Gyeongbuk province. Multiple infections were more common in women under 25 years of age than above age and precancerous lesion.