Outcomes of Venovenous Extracorporeal Membrane Oxygenation Support for Acute Respiratory Distress Syndrome in Adults
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 91-94, 2012.
Article
in English
| WPRIM
| ID: wpr-171325
ABSTRACT
BACKGROUND:
Despite improved managements for acute respiratory distress syndrome (ARDS), its mortality remains high. Extracorporeal membrane oxygenation (ECMO) has emerged as the final option for the treatment of ARDS unresponsive to conventional measures. This study describes our experiences of venovenous ECMO support for the treatment of ARDS. MATERIALS ANDMETHODS:
Between 2007 and 2010, 56 patients (aged 56.6+/-13.4 years, 43 males) received venovenous ECMO for the treatment of ARDS. The detailed clinical records were retrospectively reviewed.RESULTS:
Before the institution of ECMO support, 35 patients (55.4%) required nitric oxide inhalation, 35 patients (55.4%) received continuous renal replacement therapy, and 20 patients (35.7%) were in shock status. The median duration of ECMO support was 164 hours (range, 5 to 1,413 hours). 27 (48%) patients could be successfully weaned from ECMO. Of them, 7 (13%) survived to discharge. On logistic regression analysis, a requirement for higher inspiratory pressure before ECMO support was the only significant factor that could predict ECMO weaning failure.CONCLUSION:
The outcome of venovenous ECMO support for the treatment of ARDS was suboptimal. Further improvements in outcomes should be made through the accumulation of experience and establishment of a standardized protocol for the management of ECMO.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Respiratory Distress Syndrome
/
Shock
/
Weaning
/
Extracorporeal Membrane Oxygenation
/
Logistic Models
/
Inhalation
/
Retrospective Studies
/
Renal Replacement Therapy
/
Nitric Oxide
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
Language:
English
Journal:
The Korean Journal of Thoracic and Cardiovascular Surgery
Year:
2012
Type:
Article
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