The situations on chromosomes and dermatoglyphics of 19 children with congenital malformation at the Oloppalme hospital

ABSTRACT

19 children at the age from 2 days to 15 years old includes 15 females, 3 males and 1 hermaphrodite - The clinical examinations, health records, analysis of chromosomes and dermatoglyphics shown that In 5 cases with chromosomal aberrations + 3 cases down (2 trisomi 21 and 1 down translocation D/G) + 1 case with symtoms of male turn (chromosome Y chromosome F)+1 case hermaphrodite, karyotyp 46, XY, with muti- malformations and female phenotype. -The analysis of acrocentric- chromonomal association shown that +Frequency of acrocentric- chromosomal associations 62% + Frequency of acrocentric- chromosomal associations per cell 1.18. + The means of chromosomal association 2.13. +Frequencies of gaps, isogaps, chromosomal aberrations, chromatid aberrations are the same in comparision with the other researchers. + In all of three patients with limb malformations, there are abnormalities in dermatoglyphics