A Case of Psoriasiform Dermatitis Followed by Tumor Necrosis Factor Inhibitor Treated with Phototherapy
Journal of Rheumatic Diseases
;
: 270-274, 2013.
Article
in Korean
| WPRIM
| ID: wpr-171503
ABSTRACT
Although tumor necrosis factor (TNF)-alpha antagonist is a successful treatment modality for various autoimmune diseases, including rheumatoid arthritis (RA), ankylosing spondylitis and psoriatic arthritis, many adverse effects have been reported. Cutaneous adverse reactions of TNF-alpha antagonist include skin rash, urticaria, lupus like rash, seborrheic dermatitis and different kinds of psoriasiform dermatitis. We report a case of psoriasiform dermatitis during TNF-alpha antagonist treatment in a 50-year-old woman with RA. The patient has been treated with adalimumab. After 2 months, she developed pruritic erythematous eruption and desquamative lesions on the head and limbs, which were defined as psoriasiform change by a skin biopsy. These skin lesions are successfully treated with combination therapy, including cessation of adalimumab, corticosteroid and phototherapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phototherapy
/
Arthritis, Rheumatoid
/
Skin
/
Autoimmune Diseases
/
Urticaria
/
Biopsy
/
Tumor Necrosis Factor-alpha
/
Dermatitis, Seborrheic
/
Dermatitis
/
Exanthema
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2013
Type:
Article
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