Laboratory test for the optimal infective dosage of poliovirus in production of OPV from Sabin attenuate strains

ABSTRACT

3 types the results were evaluated according to the efficacy of obtained vaccines have shown that the mininal infective dosages of poliovirus in production of oral live poliovirus vaccine in the renal cells of monkey which given the highest efficacy were 103 TCID 50 /bottle of Roux, 104TCID/bottle of Roux and 103 TCID/ bottle of Roux for type I (strain WHO-IS-C), type II (strain IIS-90A) and type III (IIIs-79A), respectively