Unexpected Multidrug Resistance of Methicillin-Resistant Staphylococcus aureus in Urine Samples: A Single-Center Study
Korean Journal of Urology
;
: 349-353, 2014.
Article
in English
| WPRIM
| ID: wpr-17192
ABSTRACT
PURPOSE:
Infections of methicillin-resistant Staphylococcus aureus (MRSA) are becoming an increasingly concerning clinical problem. The aim of this study was to assess the development of MRSA in urine cultures in a major public university-affiliated hospital and the therapeutical and hygiene-related possibilities for reducing resistance. MATERIALS ANDMETHODS:
This study included 243 samples from patients diagnosed with MRSA infection over a period of 6 years. An agar diffusion test measured the effects of antimicrobial agents against bacteria grown in culture. The analyses were based on the guidelines of the Clinical and Laboratory Standards Institute.RESULTS:
A regression analysis was performed, which showed 100% resistance to the following antibiotics throughout the entire testing period carbapenem, cephalosporin (1st-4th generation), penicillin G, aminopenicillin, beta-lactamase, and isoxazolyl penicillin. However, a significant decrease in resistance was found for amikacin, gentamicin, clindamycin, levofloxacin, erythromycin, and mupirocin.CONCLUSIONS:
MRSA showed a decreasing trend of antimicrobial resistance, except against carbapenem, cephalosporin (1st-4th generation), penicillin G, aminopenicillin, beta-lactamase, and isoxazolyl penicillin, for which complete resistance was observed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillin G
/
Penicillins
/
Bacteria
/
Beta-Lactamases
/
Amikacin
/
Clindamycin
/
Gentamicins
/
Erythromycin
/
Mupirocin
/
Drug Resistance, Multiple
Type of study:
Practice guideline
Limits:
Humans
Language:
English
Journal:
Korean Journal of Urology
Year:
2014
Type:
Article
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