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Unexpected Multidrug Resistance of Methicillin-Resistant Staphylococcus aureus in Urine Samples: A Single-Center Study
Korean Journal of Urology ; : 349-353, 2014.
Article in English | WPRIM | ID: wpr-17192
ABSTRACT

PURPOSE:

Infections of methicillin-resistant Staphylococcus aureus (MRSA) are becoming an increasingly concerning clinical problem. The aim of this study was to assess the development of MRSA in urine cultures in a major public university-affiliated hospital and the therapeutical and hygiene-related possibilities for reducing resistance. MATERIALS AND

METHODS:

This study included 243 samples from patients diagnosed with MRSA infection over a period of 6 years. An agar diffusion test measured the effects of antimicrobial agents against bacteria grown in culture. The analyses were based on the guidelines of the Clinical and Laboratory Standards Institute.

RESULTS:

A regression analysis was performed, which showed 100% resistance to the following antibiotics throughout the entire testing period carbapenem, cephalosporin (1st-4th generation), penicillin G, aminopenicillin, beta-lactamase, and isoxazolyl penicillin. However, a significant decrease in resistance was found for amikacin, gentamicin, clindamycin, levofloxacin, erythromycin, and mupirocin.

CONCLUSIONS:

MRSA showed a decreasing trend of antimicrobial resistance, except against carbapenem, cephalosporin (1st-4th generation), penicillin G, aminopenicillin, beta-lactamase, and isoxazolyl penicillin, for which complete resistance was observed.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Penicillin G / Penicillins / Bacteria / Beta-Lactamases / Amikacin / Clindamycin / Gentamicins / Erythromycin / Mupirocin / Drug Resistance, Multiple Type of study: Practice guideline Limits: Humans Language: English Journal: Korean Journal of Urology Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Penicillin G / Penicillins / Bacteria / Beta-Lactamases / Amikacin / Clindamycin / Gentamicins / Erythromycin / Mupirocin / Drug Resistance, Multiple Type of study: Practice guideline Limits: Humans Language: English Journal: Korean Journal of Urology Year: 2014 Type: Article