Correlation Between Multifocal Electroretinography and Visual Acuity After Resolution of Diabetic Macular Edema

ABSTRACT

PURPOSE: To evaluate the prognostic value of multifocal electroretinography (mfERG) after a decrease of retinal thickness in eyes with diabetic macular edema (DME). METHODS: Sixty patients (60 eyes) underwent intravitreal injection of triamcinolone acetonide or bevacizumab for diabetic macular edema. Eyes were divided into three groups, according to foveal thickness Group A (==800 micrometer, n=20 eyes). Best-corrected visual acuity (BCVA) and mfERG responses from the most central seven hexagons were analyzed both before and after treatment. RESULTS: The pre-injection P1 amplitudes of mfERG correlated significantly with end-point BCVA in Groups A and B (p0.05) in Group C. CONCLUSIONS: The level of P1 amplitudes of mfERG may be a useful tool to predict visual outcomes after a decrease of retinal thickness in patients with diabetic macular edema.