Association between Seasonal Changes in Vitamin D and Bone Mineral Density / 대한폐경학회지
The Journal of Korean Society of Menopause
;
: 88-93, 2011.
Article
in English
| WPRIM
| ID: wpr-172084
ABSTRACT
OBJECTIVES:
Vitamin D deficiency, which causes secondary hyperparathyroidism, is considered to be a major contributor to osteoporosis. Because the serum 25-hydroxyvitamin D (25-OHD) level depend on sun exposure and, varies by season, the level of serum 25-OHD in each season at which vitamin D status can lead to changes in bone mineral density (BMD) is not known.METHODS:
A total of 2,878 women who underwent periodic health examinations at Ajou University Hospital were included in this study. We measured the serum 25-OHD concentrations using radioimmunoassay and BMDs using dual energy x-ray absorptiometry (DXA). The differences in serum 25-OHD levels among groups as a function of age, season, and BMD were tested by one-way ANOVA.RESULTS:
The serum 25-OHD level was not different based on age, but by season, with higher levels in the summer and autumn than in the winter and spring. However, the 25-OHD level did not have a significant relationship with BMD in any season.CONCLUSION:
The serum 25-OHD level represents vitamin D status at the time of testing, which is not associated with long-term changes in BMD. When the 25-OHD levels are used to make clinical decisions related to the treatment of osteoporosis, careful interpretation is required.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Seasons
/
Vitamin D
/
Vitamin D Deficiency
/
Vitamins
/
Radioimmunoassay
/
Absorptiometry, Photon
/
Bone Density
/
Solar System
/
Hyperparathyroidism, Secondary
Type of study:
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
The Journal of Korean Society of Menopause
Year:
2011
Type:
Article
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