Two Cases of Rhabdomyolysis Complicated with Doxylamine Overdose / 대한신장학회잡지
Korean Journal of Nephrology
;
: 542-546, 2000.
Article
in Korean
| WPRIM
| ID: wpr-172296
ABSTRACT
Doxylamine succinate is common over-the-counter sleep medication that is frequently involved in accidental poisonings and suicide attempts. Doxylamine overdose is generally directed at the anticholinergic effect including autonomic,and central nervous system effect and direct cardiac toxicity. Rarely, rhabdomyolysis has been reported with doxylamine overdose. We experienced two cases of rhabdomyolysis with overdose of doxylamine in 17-year-old and 31-year-old male. They were diagnosed with high levels of creatine phosphokinase in serum, myoglobin in serum and urine, and increased radionuclide uptake of muscles in (99m)Tc-MDP bone scan. Patients recovered without any complications with hydration and diuresis. Clinicians should be aware of the possibility of rhabdomyolysis in patients with doxylamine overdose.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Poisoning
/
Rhabdomyolysis
/
Suicide
/
Central Nervous System
/
Succinic Acid
/
Creatine Kinase
/
Diuresis
/
Doxylamine
/
Acute Kidney Injury
/
Muscles
Limits:
Adolescent
/
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2000
Type:
Article
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