Treatment and clinical outcome of needle-track seeding from hepatocellular carcinoma / 대한간학회지
The Korean Journal of Hepatology
;
: 106-112, 2011.
Article
in English
| WPRIM
| ID: wpr-172644
ABSTRACT
BACKGROUND/AIMS:
Needle-track seeding is a rare but important complication of diagnostic and therapeutic ultrasound (US)-guided procedures in hepatocellular carcinoma (HCC). We examined the frequency of needle-track seeding after US-guided percutaneous ethanol injection (PEI), fine-needle aspiration biopsy (FNAB), and percutaneous transhepatic biliary drainage (PTBD) in order to determine the appropriate treatment for needle-track seeding and its clinical outcome.METHODS:
We analyzed the clinical characteristics and treatment outcomes in eight patients who experienced needle-track seeding from HCC after an US-guided procedure (FNAB, PEI, or PTBD) between January 1990 and July 2004.RESULTS:
Seven (0.14%) of 5,092 patients who experienced needle-track seeding (2 after PEI, 4 after FNAB, and 1 after PTBD) during the study period and 1 other patient who experienced needle-track seeding recently were recruited for this study. Two of the eight patients underwent mass excision and the other six patients underwent en-bloc wide excision for the needle-track seeding. Tumors recurred in the needle-tracks in both patients who underwent mass excision but not in the six patients who underwent en-bloc wide excision. Mortality occurred in three patients who experienced the recurrence and progression of intrahepatic HCC.CONCLUSIONS:
The incidence of needle-track seeding after US-guided procedures in HCC was 0.14%. En-bloc wide excision seems to be the optimal treatment for minimizing the probability of tumor recurrence due to needle-track seeding.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin Neoplasms
/
Tomography, X-Ray Computed
/
Retrospective Studies
/
Carcinoma, Hepatocellular
/
Biopsy, Fine-Needle
/
Liver Neoplasms
/
Neoplasm Seeding
Type of study:
Observational study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
The Korean Journal of Hepatology
Year:
2011
Type:
Article
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