A Contrast Nephropathy in a Preterm Infant Following Preoperative Embolization of Giant Sacrococcygeal Teratoma
Childhood Kidney Diseases
;
: 26-30, 2017.
Article
in English
| WPRIM
| ID: wpr-172665
ABSTRACT
Newborn infants with huge and highly vascular sacrococcygeal teratoma (SCT) are frequently subjected to renal hypoperfusion secondary to high-output cardiac failure. Any underlying renal dysfunction is a significant risk factor for the development of contrast-induced nephropathy (CIN). However, reports on CIN in infants are rare. I report here a case of a premature infant born at 28 weeks and 3 days of gestation with a huge SCT who survived preoperative embolization and surgical resection but presented with persistent non-oliguric renal failure that was suggestive of CIN. During radiological intervention, a contrast medium had been administered at about 10 times the manufacturer-recommended dose for pediatric patients. Despite hemodynamic stabilization and normalization of urine output immediately following surgery, the patient's serum creatinine and cystatin-C levels did not return to baseline until 4 months after birth. No signs of reflux nephropathy were observed in follow-up imaging studies. Dosing guidelines for the use of a contrast medium in radiological interventions should be provided for infants or young patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Teratoma
/
Infant, Premature
/
Risk Factors
/
Follow-Up Studies
/
Creatinine
/
Parturition
/
Embolization, Therapeutic
/
Renal Insufficiency
/
Acute Kidney Injury
/
Heart Failure
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Infant
/
Infant, Newborn
/
Pregnancy
Language:
English
Journal:
Childhood Kidney Diseases
Year:
2017
Type:
Article
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