Effects of 5-Fluorouracil on Delayed Adjustment in Experimental Strabismus Surgery
Journal of the Korean Ophthalmological Society
;
: 1925-1930, 1996.
Article
in Korean
| WPRIM
| ID: wpr-173002
ABSTRACT
Adjustable sutures increased the rate of success with a single procedure, but sometimes fails because of changes in the angle of deviation which develops a few days after surgery. Therefore, the delayed adjustment was attempted;however, the postoperative adhesion following strabismus surgery make delayed adjustment impossible. We studied 45 eyes of 25 rabbits; adjustable strabismus surgery underwent a hang-back technique in the superior rectus muscle. In experimental group, a sponge was soaked in 5-Fluorouracil, and the sponge was placed between the conjunctiva and the sclera for 5 minutes during the operation. We studied the possible time of delayed adjustment and estimated the minimal forces required for the adjustment. The experimental group A (5-Fluorouracil, 50mg/ml) allowed for a 6 day delayed adjustment after surgery, control group allowed for a 2 day delayed adjustment after surgery. These results suggest that 5-Fluorouracil may valuable resource to delayed adjustment strabismus surgery by reduce postoperative adhesion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Porifera
/
Sclera
/
Sutures
/
Strabismus
/
Conjunctiva
/
Fluorouracil
Limits:
Animals
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
1996
Type:
Article
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