Improvement of Screening Accuracy of Mini-Mental State Examination for Mild Cognitive Impairment and Non-Alzheimer's Disease Dementia by Supplementation of Verbal Fluency Performance
Psychiatry Investigation
;
: 44-51, 2014.
Article
in English
| WPRIM
| ID: wpr-173021
ABSTRACT
OBJECTIVE:
This study aimed to investigate whether the supplementation of Verbal Fluency Animal category test (VF) performance can improve the screening ability of Mini-Mental State Examination (MMSE) for mild cognitive impairment (MCI), dementia and their major subtypes.METHODS:
Six hundred fifty-five cognitively normal (CN), 366 MCI [282 amnestic MCI (aMCI); 84 non-amnestic MCI (naMCI)] and 494 dementia [346 Alzheimer's disease (AD); and 148 non-Alzheimer's disease dementia (NAD)] individuals living in the community were included (all aged 50 years and older) in the study.RESULTS:
The VF-supplemented MMSE (MMSE+VF) score had a significantly better screening ability for MCI, dementia and overall cognitive impairment (MCI plus dementia) than the MMSE raw score alone. MMSE+VF showed a significantly better ability than MMSE for both MCI subtypes, i.e., aMCI and naMCI. In the case of dementia subtypes, MMSE+VF was better than the MMSE alone for NAD screening, but not for AD screening.CONCLUSION:
The results support the usefulness of VF-supplementation to improve the screening performance of MMSE for MCI and NAD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Mass Screening
/
Dementia
/
Alzheimer Disease
/
Cognitive Dysfunction
/
NAD
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Animals
Language:
English
Journal:
Psychiatry Investigation
Year:
2014
Type:
Article
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