Successful Treatment of Newly Developed, Intractable Digital Ulcers and Gangrene with Bosentan in Systemic Sclerosis
Journal of Rheumatic Diseases
;
: 193-197, 2016.
Article
in English
| WPRIM
| ID: wpr-173095
ABSTRACT
In systemic sclerosis, digital ulcers and gangrene are somewhat common clinical characteristics of obliterative vasculopathy. These manifestations increase morbidities, such as pain, infections, and acroosteolysis. However, patient responses to the appropriate treatments are often inadequate. We treated a patient with systemic sclerosis who had a refractory digital ulcer and gangrene with bosentan, an endothelin receptor antagonist, and observed improvement. Here we systematically review this case.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Scleroderma, Systemic
/
Ulcer
/
Receptors, Endothelin
/
Acro-Osteolysis
/
Gangrene
Limits:
Humans
Language:
English
Journal:
Journal of Rheumatic Diseases
Year:
2016
Type:
Article
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