A Case Report of Renal Involvement in Adult-Onset Still's Disease over Age 70
Journal of Rheumatic Diseases
;
: 364-368, 2013.
Article
in Korean
| WPRIM
| ID: wpr-173303
ABSTRACT
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disease characterized by spiking fever, arthralgia, salmon pink rash, neutrophilic leukocytosis, and multi-organ involvement. Although renal involvement may appear in some cases of adult Still's disease, onset over 70 years of age with renal involvement has not been described. We report a 73-years-old woman whose illness manifested with fever of unknown origin, massive proteinuria, and multiple lymph nodes enlargement. With proteinuria of 2,650 mg/day, a renal biopsy was performed, and histopathological evaluation yielded the diagnosis of chronic glomerulonephritis (CGN). After excluding infectious disease, malignancy, and other rheumatic disease, AOSD was diagnosed with symptoms including fever over 39.0degrees C for more than a week, leukocytosis, generalized lymphadenopathy, and negative autoantibodies. Proteinuria and fever were improved markedly by high dose glucocorticoids and methotrexate therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Salmon
/
Autoantibodies
/
Biopsy
/
Methotrexate
/
Rheumatic Diseases
/
Communicable Diseases
/
Still's Disease, Adult-Onset
/
Arthralgia
/
Diagnosis
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2013
Type:
Article
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