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Stem Cell Therapy for Neonatal Disorders: Prospects and Challenges
Yonsei Medical Journal ; : 266-271, 2017.
Article in English | WPRIM | ID: wpr-174337
ABSTRACT
Despite recent advances in neonatal medicine, neonatal disorders, such as bronchopulmonary dysplasia and intraventricular hemorrhage in preterm neonates and hypoxic ischemic encephalopathy in term neonates, remain major causes of mortality and morbidities. Promising preclinical research results suggest that stem cell therapies represent the next breakthrough in the treatment of currently intractable and devastating neonatal disorders with complex multifactorial etiologies. This review focuses primarily on the potential role of stem cell therapy in the above mentioned neonatal disorders, highlighting the results of human clinical trials and the challenges that remain to be addressed for their safe and successful translation into clinical care of newborn infants.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Stem Cells / Bronchopulmonary Dysplasia / Mortality / Hypoxia-Ischemia, Brain / Mesenchymal Stem Cells / Hemorrhage Type of study: Prognostic study Limits: Humans / Infant, Newborn Language: English Journal: Yonsei Medical Journal Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Stem Cells / Bronchopulmonary Dysplasia / Mortality / Hypoxia-Ischemia, Brain / Mesenchymal Stem Cells / Hemorrhage Type of study: Prognostic study Limits: Humans / Infant, Newborn Language: English Journal: Yonsei Medical Journal Year: 2017 Type: Article