High-Grade Prostatic Intraepithelial Neoplasia
Korean Journal of Urology
;
: 297-303, 2012.
Article
in English
| WPRIM
| ID: wpr-174431
ABSTRACT
High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing to the increase in prostate biopsy cores. Nevertheless, a literature review supports that large-volume HGPIN and multiple cores of involvement at the initial biopsy should prompt a repeat biopsy of the prostate within 1 year. No treatment is recommended for HGPIN to slow its progression to cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostate
/
Prostatic Neoplasms
/
Biopsy
/
Adenocarcinoma
/
Mass Screening
/
Prostate-Specific Antigen
/
Prostatic Intraepithelial Neoplasia
Type of study:
Screening study
Language:
English
Journal:
Korean Journal of Urology
Year:
2012
Type:
Article
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