A case of gastritis cystica profunda with early gastric cancer / 대한내과학회지

ABSTRACT

We report a rare case of adenocarcinoma with multiple gastritis cystica profunda that develope in a 56-year-old man. We found early gastric cancer at the gastric angle. And some cystic lesion was present at lesser curvature of the body. Gastrectomy was performed for confirmation and treatment. Gastritis cystica profunda (GCP) is usually characterized by multiple cystic mass in the mucosa and submucosa of the stomach. It is rare disease which is mainly found at the stoma site of gastroenterostomy. Occasionally GCP develops in the stomach without previous history of surgery. Most common feature of GCP is sessile polypoid protrusion but, submucosal tumor, giant gastric mucosal fold and pedunculated mass are found. Some evidence suggests that downward adenocystic proliferation of glands is a dysplastic or precancerous change. But we know that these submucosal cystic lesion may not be precancerous. Thus cystic mass must be distinguished from Menetrier's disease, Zollinger-Eillison's syndrome, and other malignancy.