Salmonellosis in children: Analysis of 72 Salmonella-positive culture cases during the last 10 years / 소아과
Korean Journal of Pediatrics
;
: 791-797, 2009.
Article
in Korean
| WPRIM
| ID: wpr-175068
ABSTRACT
PURPOSE:
We aimed to investigate the clinical manifestations of and antibiotic resistance in culture-proven childhood salmonellosis.METHODS:
Clinical manifestations and laboratory data of and antibiotic use in subjects with culture-proven childhood salmonellosis, who were treated at the Chonbuk National University Hospital between September 1998 and August 2008, were analyzed retrospectively. Patients with underlying diseases or concomitant illnesses were excluded.RESULTS:
We assessed a total of 72 patients. There were 68 stool culture-positive cases, 7 blood culture-positive cases, and 3 both stool culture- and blood culture-positive cases. Salmonella group D was the most frequent pathogen in stool (63.9%) and blood (71.4%) cultures. Salmonella typhi was isolated in 1 case. Of the 72 patients, 45 (62.5%) were male children, of which 29 (40.3%) were aged 15,000/microliter) and leukopenia (leukocyte count, 5 mg/dL) and erythrocyte sedimentation rate (>20 mm/h) were observed in 88.9% and 58.3% of the patients, respectively. Fifty-two (85.2%) of 61 patients who had undergone antibiotic treatment received a third-generation cephalosporin as definitive antibiotic therapy. Multidrug resistance rate was 40.0% in the first 5 years of the study and 71.4% in the last 5 years. No fatalities occurred in this series.CONCLUSION:
Children with culture-proven salmonellosis showed relatively benign clinical outcomes. Appropriate antibiotic treatment of <2 weeks is probably adequate for those without a suppurative focus of infection. The incidence of antibiotic resistant isolates was recently seen to increase.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Salmonella
/
Salmonella Infections
/
Salmonella typhi
/
Blood Sedimentation
/
C-Reactive Protein
/
Drug Resistance, Microbial
/
Incidence
/
Retrospective Studies
/
Drug Resistance, Multiple
/
Diarrhea
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Aged
/
Child
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Pediatrics
Year:
2009
Type:
Article
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