Fractional exhaled nitric oxide and forced expiratory flow between 25% and 75% of vital capacity in children with controlled asthma / 소아과
Korean Journal of Pediatrics
;
: 330-336, 2012.
Article
in English
| WPRIM
| ID: wpr-175381
ABSTRACT
PURPOSE:
Fractional exhaled nitric oxide (FeNO) and forced expiratory flow between 25% and 75% of vital capacity (FEF25-75) are not included in routine monitoring of asthma control. We observed changes in FeNO level and FEF25-75 after FeNO-based treatment with inhaled corticosteroid (ICS) in children with controlled asthma (CA).METHODS:
We recruited 148 children with asthma (age, 8 to 16 years) who had maintained asthma control and normal forced expiratory volume in the first second (FEV1) without control medication for > or =3 months. Patients with FeNO levels >25 ppb were allocated to the ICS-treated (FeNO-based management) or untreated group (guideline-based management). Changes in spirometric values and FeNO levels from baseline were evaluated after 6 weeks.RESULTS:
Ninety-three patients had FeNO levels >25 ppb. These patients had lower FEF25-75% predicted values than those with FeNO levels 25 ppb.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Spirometry
/
Vital Capacity
/
Forced Expiratory Volume
/
Nitric Oxide
Type of study:
Practice guideline
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2012
Type:
Article
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