Intracerebral Aspergillus Abscess Combined with Large Frontal Mucopyocele

ABSTRACT

Intracranial aspergillosis is rare and often fatal, and the brain is the third most frequent origine involved, precede by the lung and the gastrointestinal tract. Two routes of infection are considered important for infection of the central nervous system with aspergillus ; direct spread of infection, mostly within the paranasal sinuses, or hematogenous spread, usually originated from the lung. Paranasal sinus mucocele is a chronic expanding lesion lined by sinus mucosa and containing thickened mucus. Complication arise as a result of infection or expansion of mucoceles. Mucoceles that invade adjacent area, such as the orbits or anterior cranial fossa, can cause complication by a mass effect. The authors report their surgical experience of intracranial aspergillus abscess combined with large frontal mucopycele.