Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney
Journal of the Korean Society of Coloproctology
;
: 346-349, 2006.
Article
in Korean
| WPRIM
| ID: wpr-175632
ABSTRACT
We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Sigmoid Neoplasms
/
Colon, Sigmoid
/
Tomography, X-Ray Computed
/
Leucovorin
/
Chemotherapy, Adjuvant
/
Diagnosis
/
Drug Therapy
/
Fluorouracil
/
Kidney
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Coloproctology
Year:
2006
Type:
Article
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