Idiopathic cardiomyopathies in Korean Children: A nationwide study
Korean Circulation Journal
;
: 635-645, 2000.
Article
in Korean
| WPRIM
| ID: wpr-176016
ABSTRACT
BACKGROUND:
Although idiopathic cardiomyopathies(i-CMP) are very important in all age groups, the epidemiology of i-CMP in children has not been well defined. A retrospective study in Korean children was performed in 1998 to obtain basic data on i-CMP. MATERIAL ANDMETHOD:
The medical records of all patients aged birth to 15 years from the hospitals where pediatric cardiologists worked were reviewed to obtain information on i-CMP. Pediatric cardiologists from a total of 22 hospitals were participated in reviewing the medical records of their patients and filling up the protocol. The data were pooled to the study committee and reviewed.RESULTS:
Of the 278 cases with i-CMP, there were dilated cardiomyopathy (d-CMP) in 182 (65.4%) hypertrophic cardiomyopathy (h-CMP) in 74 (26.6%) restrictive cardiomyopathy (r-CMP) and unclassified in 17 (6.1%) and 5 (1.9%) each. The average annual occurrence of new cases as a whole was 2.65 per 100,000 (95% CI 1.5-3.7) d-CMP, 1.73/100,000/year (95% CI 0.73-2.73) h-CMP, 0.71/100,000/year (95% CI 0.35-1.07) r-CMP, 0.16/100,000/year (95% CI 0.02-0.3). The median age at the time of diagnosis was 11 months in d-CMP 3.0 years in h-CMP 6.9 years in r-CMP. The survival rate in d-CMP was 76% at 1 year, 72.5% at 2 year, 70% at 5 year. There was no difference in survival rate according to age (in d-CMP, between children less than 2 years of age and over 2 years of age (74% vs. 79% at 1 year 67% vs. 76% at 5 year, p=NS) in h-CMP, between children less than 1 year of age and over 1 year of age (84% vs. 96% at 1 year 63% vs. 81% at 5 year, p=NS)). R-CMP showed the worst survival rate (72% at 1 year, 30.2% at 5 year).CONCLUSION:
In spite of the inherent defects of retrospective analysis, this study provides the useful epidemiological data in children with i-CMP. However, more systemic approach is needed to define the nature of the i-CMP in children.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cardiomyopathy, Hypertrophic
/
Cardiomyopathy, Restrictive
/
Cardiomyopathy, Dilated
/
Medical Records
/
Epidemiology
/
Survival Rate
/
Retrospective Studies
/
Parturition
/
Diagnosis
/
Cardiomyopathies
Type of study:
Diagnostic study
/
Practice guideline
/
Observational study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
2000
Type:
Article
Similar
MEDLINE
...
LILACS
LIS