A Case of Acute Renal Failure Caused by Hyperosmolar Hyperglycemic State Induced-Rhabdomyolysis / 대한신장학회잡지
Korean Journal of Nephrology
;
: 645-649, 2006.
Article
in Korean
| WPRIM
| ID: wpr-176123
ABSTRACT
Acute renal failure is the most common complication of rhabdomyolysis. However, hyperosmolar hyperglycemic state (HHS) induced-rhabdomyolysis rarely causes acute renal failure (ARF) because HHS induces osmotic diuresis and prevents tubular necrosis. Here we report a case of acute renal failure caused by HHS-induced rhabdomyolysis in a patient with poorly controlled diabetes mellitus. A 59-year-old male was admitted with comatose mentality. He had been diagnosed with diabetes mellitus 6 months ago but had not been treated. Physical examination showed severe dehydration of oral mucosa. His laboratory findings demonstrated severe HHS, rhabdomyolysis and acute renal failure (plasam glucose 1,543 mg/dL, osmolarity 329 mOsm/L, creatine phophokinase 15,395 IU/L, lactate dehydrogenase 1,046 IU/L, creatinine 2.4 mg/dL). With adequate hydration and insulin therapy, HHS improved but rhabdomyolysis and ARF were more aggravated. With early hemodialysis treatment, he finally improved without sequale.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osmolar Concentration
/
Physical Examination
/
Rhabdomyolysis
/
Renal Dialysis
/
Coma
/
Creatine
/
Creatinine
/
Dehydration
/
Diabetes Mellitus
/
Diuresis
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2006
Type:
Article
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