Heterogeneity of Renal Pathology in Korean NIDDM Patients with Microalbuminuria / 대한내과학회지
Korean Journal of Medicine
;
: 889-895, 1998.
Article
in Korean
| WPRIM
| ID: wpr-176309
ABSTRACT
OBJECTIVE:
It was suggested that the cause of microalbuminuria is heterogeneous in NIDDM. However, only a few studies are available that investigated the renal pathology in NIDDM patients with microalbuminuria. This study was undertaken to evaluate renal pathology in Korean NIDDM patients with microalbuminuria.METHODS:
Fifty NIDDM patients with microalbuminuria and without retinopathy were undertaken renal biopsy. Renal pathologic findings were classified as follows group A, near-normal finding; group B, typical diabetic nephropathology; group C, atypical patterns of renal injury (mild glomerular change with disproportionally severe tubulointerstitial lesion, arteriolar hyalinosis or global glomerular sclerosis); group D, non-diabetic renal lesion.RESULTS:
Seventeen patients were classified into group A, 19 into group B and 8 into group C. Six patients had non-diabetic renal lesions and they were all confirmed to be IgA nephropathy. Fasting blood sugar and GFR were significantly higher in group B than in group A and group C respectively, and systolic blood pressure was higher in group C than in group A.CONCLUSION:
Renal pathology in microalbuminuric NIDDM patients without retinopathy was heterogeneous. This may explain heterogeneous clinical meaning of microalbuminuria in NIDDM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Population Characteristics
/
Biopsy
/
Blood Glucose
/
Blood Pressure
/
Fasting
/
Diabetes Mellitus, Type 2
/
Glomerulonephritis, IGA
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
1998
Type:
Article
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