A Case of Myasthenia Gravis after Allogeneic Bone Marrow Transplantation
Journal of the Korean Neurological Association
;
: 60-61, 2001.
Article
in Korean
| WPRIM
| ID: wpr-176466
ABSTRACT
A 38-year-old woman, affected by chronic myeloid leukemia, received a BMT from his HLA identical brother. A mild acute graft-versus-host disease (GVHD) developed during the first month after the BMT. A typical clinical and electrophysiological feature of myasthenia gravis (MG) developed 3 months after the BMT requiring medication with pyridostigmine and steroids. Laboratory findings including acetylcholine receptor antibody and other autoantibodies were negative. MG is a well-characterized autoimmune disease which, on rare occasions, is also diagnosed as chronic GVHD after BMT. We report a first case of MG during an acute GVHD period. Since the patient had a myasthenic symptom during an acute GVHD period and no evidence of antibody mediated autoimmunity, this is likely to be an immune complication of acute GVHD. (J Korean Neurol Assoc 19(1)60~61, 2001
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pyridostigmine Bromide
/
Autoantibodies
/
Autoimmune Diseases
/
Steroids
/
Bone Marrow
/
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
/
Acetylcholine
/
Autoimmunity
/
Bone Marrow Transplantation
/
Siblings
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS