A Case of Acute Tubular Necrosis and Hearing Loss Induced by Intravenous Administration of Ciprofloxacin / 대한내과학회지
Korean Journal of Medicine
;
: 491-495, 2014.
Article
in Korean
| WPRIM
| ID: wpr-176487
ABSTRACT
Ciprofloxacin is a broad-spectrum antibiotic used to treat a variety of infections. However, acute kidney injury is a rarely reported side effect. Ciprofloxacin-related nephrotoxicity typically manifests as acute tubulointerstitial nephritis. To the best of our knowledge, few cases of acute tubular necrosis as a complication of ciprofloxacin have been reported to date. We herein describe a case involving a 41-year-old woman treated with intravenous ciprofloxacin at 200 mg twice daily for gastroenteritis. One day after initiation of treatment, her serum creatinine level increased from 0.95 to 3.83 mg/dL and she experienced impaired hearing. Five days later, renal biopsy demonstrated acute tubular necrosis. The acute tubular necrosis encountered in this patient resolved; however, short-term hemodialysis was required. This is the first reported case of acute kidney injury associated with ciprofloxacin use in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Biopsy
/
Ciprofloxacin
/
Renal Dialysis
/
Creatinine
/
Acute Kidney Injury
/
Administration, Intravenous
/
Gastroenteritis
/
Hearing
/
Hearing Loss
/
Korea
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2014
Type:
Article
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